Dihydro-benzo [B] [1,4] diazepin-2-one derivatives

US6548495B2 · kind B2 · utility

Assignee

• Hoffmann-La Roche Inc. · US

Inventors

• Geo Adam · Schopfheim, DE
• Erwin Goetschi · Reinach, CH
• Vincent Mutel · Mulhouse, FR
• Juergen Wichmann · Basel, CH
• Thomas Woltering · Freiburg (Elbe), DE

Key dates

• Filing date: Apr 3, 2002
• Grant date: Apr 15, 2003
• Expiry date: Apr 3, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/10
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention is a dihydro-benzo[b][1,4]diazepin-2-one derivative of the formula wherein R1, R2, R3 and Y are as defined in the specification. The invention includes pharmaceutical compositions containing these compounds, a process for their preparation and a method of treatment or prevention of acute and/or chronic neurological disorders by administering an effective amount of the compound of formula I or a pharmaceuticall acceptable salt thereof.