Basal cell carcinoma tumor supressor gene

US6552181B1 · kind B1 · utility

Assignee

• The United States of America, as represented by the Department of Health and Human Services · US

Inventors

• Michael Dean · Frederick, US
• Heidi Eve Hahn · Washington, US
• Carol Wicking · Brisbane, AU
• Jeffrey Christiansen · Brisbane, AU
• Peter G. Zaphiropoulos · Tullinge, SE
• Mae R. Gailani · Guilford, US
• Susan M. Shanley · Brisbane, AU
• Abirami Chidambaram · Frederick, US
• Igor Vorechovsky · Southampton, GB
• Erika Holmberg-Lindstrom · Täby, SE
• Anne Birgitte Unden · Huddinge, SE
• Susan Alana Gillies · Caboolture, AU
• Kylie Negus · Brisbane, AU
• Ian SMYTH · Brisbane, AU
• Carol L. Pressman · Houston, US
• David J. Leffell · New Haven, US
• Bernard Gerrard · Frederick, US
• Alisa Goldstein · Rockville, US
• Brandon Wainwright · Brisbane, AU
• Rune Toftgard · Skärholmen, SE
• Georgia Chenevix-Trench · Brisbane, AU
• Allen E. Bale · Northford, US

Key dates

• Filing date: May 16, 1997
• Grant date: Apr 22, 2003
• Expiry date: May 16, 2017

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S530/842
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention provides for a tumor suppressor gene inactivation of which is a causal factor in nevoid basal cell carcinoma syndrome and various sporadic basal cell carcinomas. The NBCCS gene is a homologue of the Drosophila patched (ptc) gene.