Azabicyclic amine derivatives and their use as therapeutic agents
US6555552B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 1, 2002 |
| Grant date | Apr 29, 2003 |
| Priority date | — |
| Expiry date | Apr 1, 2022 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01F11/003
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates compounds of the formula (I): whereinX represents hydrogen or a C1-4alkyl group optionally substituted by a hydroxy group;Y represents hydrogen, C1-6alkyl or C3-7cycloalkyl;Z is —CR9R10CH2— or —CH2CR9R10—;R represents hydrogen, fluorine, hydroxy, C1-6alkyl or C1-6alkoxy;and R1, R2, R3, R4, R5 and R6 are as defined herein.The compounds are of particular use in the treatment of depression, anxiety, pain, inflammation, migraine, emesis or postherpetic neuralgia.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.