Patent · US Expired

Azabicyclic amine derivatives and their use as therapeutic agents

US6555552B2 · kind B2 · utility

1Cited by
1References
19Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 1, 2002
Grant dateApr 29, 2003
Priority date
Expiry dateApr 1, 2022

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01F11/003
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present invention relates compounds of the formula (I): whereinX represents hydrogen or a C1-4alkyl group optionally substituted by a hydroxy group;Y represents hydrogen, C1-6alkyl or C3-7cycloalkyl;Z is —CR9R10CH2— or —CH2CR9R10—;R represents hydrogen, fluorine, hydroxy, C1-6alkyl or C1-6alkoxy;and R1, R2, R3, R4, R5 and R6 are as defined herein.The compounds are of particular use in the treatment of depression, anxiety, pain, inflammation, migraine, emesis or postherpetic neuralgia.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.