Peptides blocking vascular endothelial growth factor (VEGF)-mediated angiogenesis, polynucleotides encoding said peptides and methods of use thereof
US6559126B2 · kind B2 · utility
63Cited by
2References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 2, 2001 |
| Grant date | May 6, 2003 |
| Priority date | — |
| Expiry date | Apr 2, 2021 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/475
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides peptides which can interact with VEGF and inhibit VEGF interaction with KDR or anti-VEGF antibody thereby inhibiting VEGF mediated angiogenesis or angiogeneis related diseases, polynucleotide encoding the peptides, vectors containing the polynucleotides, pharmaceutical compositions containing the peptides, and methods of inhibiting angiogenesis with the peptides.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.