Ureido derivatives of poly-4-amino-2-carboxy-1-methyl pyrrole compounds for inhibition of inflammation

US6562859B1 · kind B1 · utility

Assignee

• The United States of America, as represented by the Department of Health and Human Services · US

Inventors

• O. M. Zack Howard · Frederick, US
• Joost Oppenheim · Bethesda, US
• William Murphy · Reno, US
• Edward A. Sausville · Silver Spring, US

Key dates

• Filing date: Aug 4, 2000
• Grant date: May 13, 2003
• Expiry date: Aug 4, 2020

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K31/4025
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A method of using a ureido derivative of a poly-4-amino-2-carboxy-1-methyl pyrrole or a pharmaceutically acceptable salt thereof to inhibit inflammation, particularly non-TNF-&agr; dependent inflammation, in a mammal.