Cyclin dependent kinase mutants, and diagnostic and therapeutic uses related thereto
US6566054B1 · kind B1 · utility
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11Claims
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Key dates
| Filing date | Aug 30, 1996 |
| Grant date | May 20, 2003 |
| Priority date | — |
| Expiry date | Mar 17, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/158
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to the discovery in eukaryotic cells, particularly mammalian cells, of mutant cyclin dependent kinase (CDK) proteins. These proteins fail to bind to CDK-inhibitory proteins and thus lead to aberrant cell growth. Herein, screening assays are described to identify CDK mutant proteins and the uses of these mutant proteins as tumor vaccines is described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.