Methods for determining metastatic potential of breast cancer cells by detecting GSEF gene product expression
US6566063B1 · kind B1 · utility
5Cited by
1References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 12, 2000 |
| Grant date | May 20, 2003 |
| Priority date | — |
| Expiry date | May 12, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/136
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention features methods for detection of metastatic and potentially metastatic cancerous cells by detection of expression of a gland-specific Ets transcription factor (GSEF) sequence, which encodes an Ets-domain containing protein. The invention also features methods and compositions for modulation of the polypeptide and/or gene activity for prophylactic and therapeutic purposes, such as inhibition of progression of a cell to a metastatic cancerous cell.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.