Methods of using VEGF-related protein
US6576608B1 · kind B1 · utility
49Cited by
7References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 17, 1999 |
| Grant date | Jun 10, 2003 |
| Priority date | — |
| Expiry date | May 17, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A human VEGF-related protein (VRP) has been identified and isolated that binds to, and stimulates the phosphorylation of, the receptor tyrosine kinase Flt4. The VRP is postulated to be a third member of the VEGF protein family. Also provided are antibodies that bind to VRP and neutralize a biological activity of VRP, compositions containing the VRP or antibody, methods of use, chimeric polypeptides, and a signal polypeptide for VRP.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.