Drosophila homologues of genes and proteins implicated in cancer and methods of use
US6579701B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 14, 2000 |
| Grant date | Jun 17, 2003 |
| Priority date | — |
| Expiry date | Dec 14, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/43581
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Novel nucleic acids that are homologs of genes implicated in cancer are described that have been isolated from Drosophila melanogaster. These novel nucleic acids can be used to genetically modify metazoan invertebrate organisms, such as insects and worms, or cultured cells, resulting in novel gene expression or mis-expression. The genetically modified organisms or cells can be used in screening assays to identify candidate compounds which are potential pesticidal agents or therapeutics that interact with gene products implicated in cancer. They can also be used in methods for studying gene activity and identifying other genes that modulate the function of, or interact with, genes implicated in cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.