Patent · US Expired

Triazolo-pyridazine derivatives as ligands for GABA receptors

US6579875B1 · kind B1 · utility

9Cited by
7References
20Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 28, 2000
Grant dateJun 17, 2003
Priority date
Expiry dateJun 28, 2020

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P43/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

1,2,4-triazolo[4,3-b]pyridazine derivatives, possessing a fluoro-substituted phenyl ring at the 3-position and a heteroaryl-alkoxy moiety at the 6-position, are selective ligands for GABAA receptors, in particular having high affinity for the &agr;2 and/or &agr;3 subunit thereof, are useful in the treatment of anxiety and convulsions.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.