Methods for making recombinant proteins using apoptosis inhibitors
US6586206B1 · kind B1 · utility
19Cited by
1References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 25, 2000 |
| Grant date | Jul 1, 2003 |
| Priority date | — |
| Expiry date | Sep 25, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2710/14022
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention provided improved methods of making and producing recombinant proteins in in vitro cultures of host cells using apoptosis inhibitors. The use of one or more apoptosis inhibitors in the methods can reduce apoptosis in the cell cultures and markedly improve yield of the desired recombinant proteins.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.