Microanalytical device containing a membrane for molecular identification
US6607644B1 · kind B1 · utility
Assignee
Inventor
Key dates
| Filing date | Oct 31, 2000 |
| Grant date | Aug 19, 2003 |
| Priority date | — |
| Expiry date | Jul 18, 2021 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/521
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention provides a microanalytical device for analyzing a fluid sample containing at least one analyte molecule. The device is constructed from a substrate and a cover plate each having a substantially planar surface and a microchannel formed therein. The cover plate is placed over the substrate such that the cover plate microchannel is arranged in opposing relationship with the substrate microchannel. A membrane is interposed between the substrate and the cover and has at least one pore sized to allow passage of the analyte molecule from the substrate microchannel to the cover plate microchannel. An analyte altering moiety is attached to an interior surface of the pore and is capable of chemically altering the analyte molecule. Also disclosed are a method for chemically altering and transporting an analyte molecule in a fluid and a method for identifying a plurality of biomolecules.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.