Conjugate vaccine for nontypeable Haemophilus influenzae

US6607725B2 · kind B2 · utility

Assignee

• The United States of America, as represented by the Department of Health and Human Services · US

Inventors

• Xin Gu · San Francisco, US
• Chao-Ming Tsai · Bethesda, US
• David J. Lim · Pasadena, US
• John B. Robbins · New York, US

Key dates

• Filing date: Feb 20, 2001
• Grant date: Aug 19, 2003
• Expiry date: Jul 8, 2021

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S435/851
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A conjugate vaccine for Nontypeable Haemophilus influenzae comprising lipooligosaccharide from which esterified fatty acids have been removed conjugated to an immunogenic carrier. The vaccine is useful for prevention of otitis media and respiratory infections in mammals.