Oligoribonucleotides with enzymatic activity
US6617438B1 · kind B1 · utility
63Cited by
26References
27Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 30, 1999 |
| Grant date | Sep 9, 2003 |
| Priority date | — |
| Expiry date | Dec 30, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/346
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel nucleotide triphosphates, methods of synthesis and process of incorporating these nucleotide triphosphates into oligonucleotides, and isolation of novel nucleic acid catalysts (e.g., ribozymes) are disclosed. Also, described are the use of novel enzymatic nucleic acid molecules to inhibit HER2/neu/ErbB2 gene expression and their applications in human therapy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.