OB protein-polymer chimeras
US6620413B1 · kind B1 · utility
58Cited by
40References
25Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 27, 1996 |
| Grant date | Sep 16, 2003 |
| Priority date | — |
| Expiry date | Dec 27, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention concerns long-half derivative of the obesity protein OB. The invention specifically concerns OB protein-immunoglobulin chimeras and polyethylene glycol (PEG)-OB derivatives, which have extended half-life as compared to the corresponding native OB proteins. The invention further relates to methods for treating obesity by using the long half-life derivatives of OB.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.