Human anti-factor IX/IXa antibodies
US6624295B1 · kind B1 · utility
8Cited by
1References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 26, 1999 |
| Grant date | Sep 23, 2003 |
| Priority date | — |
| Expiry date | Aug 26, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/92
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides for the isolation, identification, synthesis, expression and purification of antibodies reactive with factor IX (FIX)/factor IXa (IXa). In particular aspects, the invention provides human antibodies reactive with the human FIX Gla domain. The invention further provides compositions especially pharmaceutical compositions, articles of manufacture, and methods of inhibiting the activation of-FIX and inhibiting FIX/IXa dependent coagulation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.