Patent · US Expired

Substituted phenyl-piperidine methanone compounds

US6642226B2 · kind B2 · utility

7Cited by

3References

25Claims

0Family size

Assignee

Hoffmann-La Roche Inc. · US

Inventors

Sabine Kolczewski · Lörrach, DE
Stephan Roever · Inzlingen, DE
Patrick Schnider · Bottmingen, CH

Key dates

Filing date	Jan 25, 2002
Grant date	Nov 4, 2003
Priority date	—
Expiry date	Jan 25, 2022

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D401/04
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to compounds of the formula wherein R1 is optionally substituted phenyl, morpholinyl, piperazinyl, pyrrolidinyl, piperidinyl or is thiomorpholinyl, 1-oxo-thiomorpholinyl or 1,1-dioxothiomorpholinyl. These compounds have a good affinity to the NK-1 receptor and they are therefore suitable in the control or treatment of diseases, related to this receptor.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.