Pellets having a core coated with an antifungal and a polymer

US6663901B1 · kind B1 · utility

Assignee

• Janssen Pharmaceutica NA · BE

Inventors

• Paul Marie Victor Gilis · Beerse, BE
• Valentin Florent de Conde · Lommel, BE
• Roger Petrus Gerebern Vandecruys · Westerlo, BE

Key dates

• Filing date: Jun 27, 2000
• Grant date: Dec 16, 2003
• Expiry date: Jun 27, 2020

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P31/10
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention is concerned with pellets comprising a 710-1180 &mgr;m (16-25 mesh) sugar core, a coating film of a water-soluble polymer and an antifungal agent, and a seal coating layer wherein the residual concentration of dichloromethane is below 600 ppm; pharmaceutical dosage forms comprising said pellets and a method of preparing said pellets.