Nucleic acid molecules with novel chemical compositions capable of modulating gene expression
US6673611B2 · kind B2 · utility
103Cited by
30References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 25, 2001 |
| Grant date | Jan 6, 2004 |
| Priority date | — |
| Expiry date | May 25, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/346
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to novel chemically-modified nucleic acid molecules having specific formulae that exhibit increased resistance to nucleases and increased binding affinity to target nucleic acid molecules. The invention further relates to methods of modulating gene expression using the novel chemically modified nucleic acid molecules, and compositions and cells comprising said molecules.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.