Prodrug activation using catalytic antibodies
US6677435B2 · kind B2 · utility
73Cited by
1References
5Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 18, 2001 |
| Grant date | Jan 13, 2004 |
| Priority date | — |
| Expiry date | Jun 18, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a compound that includes an active therapeutic agent attached to a blocking moiety that is sensitive to the catalytic action of molecules having retro-aldol and retro-Michael catalytic activity, methods for making such compounds and methods of converting such compounds to active therapeutic agents using molecules having aldolase activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.