High throughput method and system for screening candidate compounds for activity against target ion channels
US6686193B2 · kind B2 · utility
186Cited by
32References
42Claims
0Family size
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Key dates
| Filing date | Mar 12, 2001 |
| Grant date | Feb 3, 2004 |
| Priority date | — |
| Expiry date | Mar 12, 2021 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/6872
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Drug candidate screening methods are applied to discover compounds with activity against ion channel targets. The method may include modulating the transmembrane potential of host cells in a plurality of sample wells with a repetitive application of electric fields so as to set the transmembrane potential to a level corresponding to a pre-selected voltage dependent state of a target ion channel.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.