Antiviral compounds and methods of administration
US6686462B2 · kind B2 · utility
8Cited by
8References
10Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Feb 28, 1997 |
| Grant date | Feb 3, 2004 |
| Priority date | — |
| Expiry date | Feb 28, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H19/20
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention provides lipophilic phosphonoacid/nucleoside conjugates that exhibit exceptional antiviral activity, including activity against drug-resistant HIV strains. Compounds of the invention include phosphonoacid/nucleoside conjugates where the carboxyl group and phosphonyl groups of the phosphonacid are esterified whereby the compound contains at least one lipophilic group and at least one nucleoside group.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.