Adenoviral vector with a deletion in the E1A coding region expressing a hetorologous protein
US6696420B1 · kind B1 · utility
3Cited by
1References
24Claims
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Key dates
| Filing date | Jul 20, 1993 |
| Grant date | Feb 24, 2004 |
| Priority date | — |
| Expiry date | Jul 20, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2730/10134
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Recombinant DNA modified by a nucleotide sequence coding for a specific polypeptide sequence whose expression is sought, this recombinant DNA being appropriate to the transformation of eucaryotic cell lines, notably human or animal, the endogenous polymerases of which are susceptible of recognizing the adenovirus promoters. The DNA according to the invention is more particularly characterized by the fact that the said insertion nucleotide sequence is placed under the direct control of the early promoter of the E1A region of the genome of adenovirus.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.