Patent · US Expired

Use of 2-amino-thiazoline derivatives as inhibitors of inducible NO-synthase

US6699867B2 · kind B2 · utility

2Cited by

0References

9Claims

0Family size

Assignee

AVENTIS PHARMA S.A. · FR

Inventors

Antony Bigot · Massy, FR
Jean-Christophe Carry · Saint-Maur-des-Fossés, FR
Serge Mignani · Livry-Gargan, FR

Key dates

Filing date	Nov 8, 2002
Grant date	Mar 2, 2004
Priority date	—
Expiry date	Nov 8, 2022

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D417/14
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to the use of 2-amino-thiazoline derivatives of formula (I): in which either Y is a methylene (CH2) and X is chosen from the following groups: O, NH, (C1-C4) N-Alkyl, N-Bn, N-Ph, N-(2-Py), N-(3-Py), N-(4-Py), N-2-pyrimidyl, N-5-pyrimidyl, S, SO, SO2, CH2 or CHPh; or Y is a carbonyl (C&boxH;O) and X is chosen from the following groups: NH, N-Ph, N-(2-Py), N-(3-Py), N-(4-Py), N-2-pyrimidyl or N-5-pyrimidyl or pharmaceutically acceptable salts thereof as inhibitors of inducible NO-synthase.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.