Generation of an immune response to a pathogen
US6710035B2 · kind B2 · utility
27Cited by
14References
26Claims
0Family size
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Key dates
| Filing date | Dec 2, 1999 |
| Grant date | Mar 23, 2004 |
| Priority date | — |
| Expiry date | Dec 2, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2740/16122
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for delivering an isolated polynucleotide to the interior of a cell in a vertebrate, comprising the interstitial introduction of an isolated polynucleotide into a tissue of the vertebrate where the polynucleotide is taken up by the cells of the tissue and exerts a therapeutic effect on the vertebrate. The method can be used to deliver a therapeutic polypeptide to the cells of the vertebrate, to provide an immune response upon in vivo translation of the polynucleotide, to deliver antisense polynucleotides, to deliver receptors to the cells of the vertebrate, or to provide transitory gene therapy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.