Crystalline antifungal polymorph
US6713481B1 · kind B1 · utility
4Cited by
6References
5Claims
0Family size
Inventors
Key dates
| Filing date | Oct 5, 1998 |
| Grant date | Mar 30, 2004 |
| Priority date | — |
| Expiry date | Sep 25, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D233/56
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The crystalline polymorph Form I of (−)-4-[4-[4-[4-[[(2R-cis)-5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methoxy]phenyl]-1-piperazinyl]phenyl-2,4-dihydro-2-[(S)-1-ethyl-2(S)-hydroxylpropyl]-3H-1,2,4-triazol-3-one represented by the formula I pharmaceutical compositions containing such a polymorph and methods of using such a polymorph to treat fungal infections in mammals are disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.