High affinity TGF&bgr; nucleic acid ligands and inhibitors
US6713616B2 · kind B2 · utility
7Cited by
6References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 23, 2001 |
| Grant date | Mar 30, 2004 |
| Priority date | — |
| Expiry date | Feb 23, 2021 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/976
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods are described for the identification and preparation of high-affinity nucleic acid ligands to TGF&bgr;2. Included in the invention are specific RNA ligands to TGF&bgr;2 identified by the SELEX method. Also included are RNA ligands that inhibit the interaction of TGF&bgr;2 with its receptor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.