Patent · US Expired

Barbituric acid derivatives

US6716845B2 · kind B2 · utility

0Cited by

1References

9Claims

0Family size

Assignee

Hoffmann-La Roche Inc. · US

Inventors

Dagmar Geppert · Penzberg, DE
Frank Grams · Mannheim, DE
Hans-Willi Krell · Penzberg, DE
Herbert Leinert · Heppenheim, DE
Ernesto Menta · Parma, IT
Gerd Zimmermann · Eckental, DE

Key dates

Filing date	Feb 25, 2002
Grant date	Apr 6, 2004
Priority date	—
Expiry date	Apr 12, 2022

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D239/62
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention pertains to derivatives of 5,5-disubstituted pyrimidine-2,4,6,-trianones having the formula: wherein R1, R2, R3, and R4 are described herein. These compounds have antitumor and antimetastatic activity.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.