Isolated peptides corresponding to amino acid sequences of NY-ESO-1, which bind to MHC Class I and MHC Class II molecules, and uses thereof

US6723832B1 · kind B1 · utility

Assignees

• LUDWIG INSTITUTE FOR CANCER RESEARCH LTD · GB
• Memorial Sloan Kettering Cancer Center · US
• ACADEMISCH ZIEKENHUIS LEIDEN (H.O.D.N. LUMC) GMBH · NL
• Cornell Research Foundation, Inc. · US

Inventors

• Alexander Knuth · Frankfurt am Main, DE
• Elke Jager · Frankfurt am Main, DE
• Yao-Tseng Chen · New York, US
• Matthew Scanlan · Princeton Junction, US
• Ali Gure · New York, US
• Gerd Ritter · New York, US
• Lloyd J. Old · New York, US
• Jan Wouter Drijfhout · Leiden, NL

Key dates

• Filing date: Oct 2, 1998
• Grant date: Apr 20, 2004
• Expiry date: Oct 2, 2018

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K39/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to peptides which bind to MHC Class I and to MHC Class II molecules. These peptides are useful in different therapeutic and diagnostic contexts.