Patent · US Expired

Azabicyclic ether derivatives and their use as therapeutic agents

US6727249B2 · kind B2 · utility

1Cited by
2References
16Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 1, 2002
Grant dateApr 27, 2004
Priority date
Expiry dateMay 4, 2022

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D451/02
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present invention relates compounds of the formula (I): whereinX represents hydrogen, C1-4alkyl optionally substituted by a hydroxy, methoxy or benzyloxy group, or CO2(C1-2alkyl);Z is —CR9R10CH2— or —CH2CR9R10—;and R1, R2, R3, R4, R5 and R6 are as defined herein.The compounds are of particular use in the treatment or prevention of depression, anxiety, pain, inflammation, migaine, emesis or postherpetic neuralgia.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.