Method and product for the sequence determination of peptides using a mass spectrometer

US6750061B2 · kind B2 · utility

Assignees

• The Rockefeller University · US
• THE SCRIPPS RESEARCH INSTITUTE · US

Inventors

• Brian T. Chait · New York, US
• Ronald Beavis · Winnipeg, CA
• Rong Wang · Mianyang, CN
• Stephen B. H. Kent · Melbourne, AU

Key dates

• Filing date: Apr 5, 2001
• Grant date: Jun 15, 2004
• Expiry date: Jan 31, 2022

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10T436/255
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Method is described for sequencing polypeptides by forming peptide ladders comprising a series of polypeptides in which adjacent members of the series vary by one amino acid residue and determining the identity and position of each amino acid in the polypeptide by mass spectroscopy.