Detection of biological molecules using boronate-based chemical amplification and optical sensors
US6750311B1 · kind B1 · utility
202Cited by
41References
13Claims
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Key dates
| Filing date | Dec 14, 1999 |
| Grant date | Jun 15, 2004 |
| Priority date | — |
| Expiry date | Dec 14, 2019 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T428/31551
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods are provided for the determination of the concentration of biological levels of polyhydroxylated compounds, particularly glucose. The methods utilize an amplification system that is an analyte transducer immobilized in a polymeric matrix, where the system is implantable and biocompatible. Upon interrogation by an optical system, the amplification system produces a signal capable of detection external to the skin of the patient. Quantitation of the analyte of interest is achieved by measurement of the emitted signal.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.