C12 modified erythromycin macrolides and ketolides having antibacterial activity

US6756359B2 · kind B2 · utility

Assignee

• Chiron Corporation · US

Inventors

• Daniel Chu · Santa Clara, US
• Matthew Burger · Belmont, US
• Xiaodong Lin · Walnut Creek, US
• Georgia Law Carroll · Walnut Creek, US
• Jacob J. Plattner · Libertyville, US
• Alice Rico · Castro Valley, US

Key dates

• Filing date: Jul 3, 2002
• Grant date: Jun 29, 2004
• Expiry date: Jul 3, 2022

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Antimicrobial macrolide compounds are provided having formulas II: as well as pharmaceutically acceptable salts, esters or prodrugs thereof; pharmaceutical compositions comprising such compounds; methods of treating bacterial infections by the administration of such compounds; and processes for the preparation of the compounds.