Method for the quantitation of alphavirus replicon particles
US6767699B2 · kind B2 · utility
34Cited by
22References
5Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 31, 2001 |
| Grant date | Jul 27, 2004 |
| Priority date | — |
| Expiry date | May 31, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2770/36151
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods of production and purification for viruses and virus-derived vectors, including those related to alphaviruses, are disclosed. In one aspect, methods of purification that subject alphavirus replicon particle preparations to one or more steps of chromatographic purification, such as using an ion exchange resin, are provided. Also disclosed are methods of characterizing alphavirus replicon particles and utilizing these materials for vaccines and gene-based therapeutics.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.