Quinoline derivatives

US6787558B2 · kind B2 · utility

Assignee

• Hoffmann-La Roche Inc. · US

Inventors

• Michael G. Klug · Brooklyn Park, US
• Patrizio Mattei · Riehen, CH
• Werner Mueller · Cologne, DE
• Werner Neidhart · Hagenthal-le-Bas, FR
• Matthias Nettekoven · Weil am Rhein, DE
• Philippe Pflieger · Schwoben, FR
• Jean-Marc Plancher · Rixheim, FR

Key dates

• Filing date: Sep 19, 2002
• Grant date: Sep 7, 2004
• Expiry date: Sep 19, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D405/14
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds of formula I as well as pharmaceutically acceptable salts and esters thereof, wherein R1, R2, R3, A1 and A2 have the significance given in claim 1, can be used in the form of pharmaceutical preparations for the treatment or prevention of arthritis, cardiovascular diseases, diabetes, renal failure, eating disorders and obesity.