Process for the preparation of oligonucleotides
US6809195B1 · kind B1 · utility
22Cited by
11References
40Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 16, 2000 |
| Grant date | Oct 26, 2004 |
| Priority date | — |
| Expiry date | Aug 22, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H19/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention discloses methods for synthesizing oligomeric compounds. The methods include a modified phosphoramidite protocol wherein the oxidation and capping steps are combined into a single step. The methods result in increased efficiency and are especially amenable to the large scale synthesis of oligomeric compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.