Methods for encapsulating plasmids in lipid bilayers
US6815432B2 · kind B2 · utility
303Cited by
16References
20Claims
0Family size
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Key dates
| Filing date | Feb 24, 2003 |
| Grant date | Nov 9, 2004 |
| Priority date | — |
| Expiry date | Feb 24, 2023 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S977/907
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Plasmid-lipid particles which are useful for transfection of cells in vitro or in vivo are described. The particles can be formed using either detergent dialysis methods or methods which utilize organic solvents. The particles are typically 65-85 nm, fully encapsulate the plasmid and are serum-stable.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.