Protein formulation
US6821515B1 · kind B1 · utility
113Cited by
98References
23Claims
0Family size
Assignee
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Key dates
| Filing date | Aug 25, 2000 |
| Grant date | Nov 23, 2004 |
| Priority date | — |
| Expiry date | Aug 25, 2020 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/81
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A stable lyophilized protein formulation is described which can be reconstituted with a suitable diluent to generate a high protein concentration reconstituted formulation which is suitable for subcutaneous administration. For example, anti-IgE and anti-HER2 antibody formulations have been prepared by lyophilizing these antibodies in the presence of a lyoprotectant. The lyophilized mixture thus formed is reconstituted to a high protein concentration without apparent loss of stability of the protein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.