Viral vector encoding pigment epithelium-derived factor
US6821775B1 · kind B1 · utility
13Cited by
14References
15Claims
0Family size
Assignee
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Key dates
| Filing date | Jun 23, 2000 |
| Grant date | Nov 23, 2004 |
| Priority date | — |
| Expiry date | Jun 23, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2799/022
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a viral vector comprising a nucleic acid sequence encoding pigment epithelium-derived factor (PEDF) or a therapeutic fragment thereof. The nucleic acid sequence is operably linked to regulatory sequences necessary for expression of PEDF or a therapeutic fragment thereof. Preferably, the viral vector is an adenoviral vector or an adeno-associated viral vector. Also preferably, the viral vector further comprises one or more additional nucleic acid sequences encoding therapeutic substances other than PEDF.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.