Antigen presenting system and methods for activation of T-cells
US6828150B2 · kind B2 · utility
6Cited by
0References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 8, 2002 |
| Grant date | Dec 7, 2004 |
| Priority date | — |
| Expiry date | Oct 8, 2022 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/827
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to synthetic antigen-presenting matrices, their methods of making and their methods of use. One such matrix is cells that have been transfected to produce MHC antigen-presenting molecules and assisting molecules such as co-stimulatory molecules. The matrices can be used to activate CD8+ T-cells to produce cytokines and become cytotoxic.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.