Process for making antifusogenic fusion peptides that form inclusion bodies

US6858410B2 · kind B2 · utility

Assignee

• Hoffmann-La Roche Inc. · US

Inventors

• Eva Hoess · Starnberg, DE
• Thomas Meier · Cherbourg, FR
• Gabriele Pestlin · Birkenfeld, DE
• Friedrich Popp · Penzberg, DE
• Klaus Reichert · Oberhausen, DE
• Rainer Schmuck · Benediktbeuern, DE
• Bernd Schneidinger · Starnberg, DE
• Christoph Seidel · Weilheim, DE
• Wilhelm Tischer · Peißenberg, DE

Key dates

• Filing date: May 30, 2002
• Grant date: Feb 22, 2005
• Expiry date: May 30, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2740/16122
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

A process is provided for producing an antifusogenic peptide by producing a fusion peptide of from about 14 amino acids up to 70 amino acids in a prokaryotic host cell under conditions in which inclusion bodies are formed. The antifusogenic peptide recovered from the inclusion bodies is a fragment cleaved from the fusion peptide which comprises an antifusogenic peptide.