Microparticles with adsorbent surfaces, methods of making same, and uses thereof
US6884435B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Jul 29, 1999 |
| Grant date | Apr 26, 2005 |
| Priority date | — |
| Expiry date | Jul 29, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2770/24234
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed to microparticles, to microparticle compositions containing the same, to methods of forming the same, and to uses for the same, including use for a vaccine, for raising an immune response, for treatment of a disease and for diagnosis of a disease. The microparticles comprise a biodegradable polymer, such as a poly(α-hydroxy acid), a polyhydroxy butyric acid, a polycaprolactone, a polyorthoester, a polyanhydride, or a polycyanoacrylate, and a detergent selected from a cationic detergent and an anionic detergent. The microparticles further comprise an antigen adsorbed on the surface of the microparticle.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.