Patent · US Expired

Anti-VEGF antibodies

US6884879B1 · kind B1 · utility

319Cited by
5References
14Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 6, 1997
Grant dateApr 26, 2005
Priority date
Expiry dateAug 6, 2017

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2317/73
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Humanized and variant anti-VEGF antibodies and various uses therefor are disclosed. The anti-VEGF antibodies have strong binding affinities for VEGF; inhibit VEGF-induced proliferation of endothelial cells in vitro; and inhibit tumor growth in vivo.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.