IL-1/TNF-α-activated kinase (ITAK), and methods of making and using the same

US6913893B2 · kind B2 · utility

Assignee

• IMMUNEX CORPORATION · US

Inventors

• John E. Sims · Seattle, US
• G. Duke Virca · Bellevue, US
• Timothy Bird · Bainbridge Island, US
• Dirk M. Anderson · Seattle, US

Key dates

• Filing date: Feb 21, 2003
• Grant date: Jul 5, 2005
• Expiry date: Sep 5, 2023

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N9/1205
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

Purified and isolated IL-1/TNF-α-activated kinase (ITAK), nucleic acids encoding ITAK, processes for production of recombinant forms of ITAK, pharmaceutical compositions containing ITAK, and use of ITAK in therapies and in various assays, including assays to detect antagonists and agonists of ITAK are provided.