Substituted tetrahydroisoquinolines as C5a receptor modulators
US6916830B2 · kind B2 · utility
3Cited by
0References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 15, 2004 |
| Grant date | Jul 12, 2005 |
| Priority date | — |
| Expiry date | Apr 15, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D495/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Substituted tetrahydroisoquinolines and related compounds are provided. Such compounds are ligands that may be used to modulate C5a receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological C5a receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using them to treat such disorders are provided, as are methods for using such ligands for receptor localization studies:
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.