Sulfonate substituted pyrazol pyridine derivatives

US6919345B2 · kind B2 · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Johannes-Peter Stasch · Wuppertal, DE
• Achim Feurer · Wilhelmsfeld, DE
• Stefan Weigand · Wuppertal, DE
• Elke Stahl · Bensberg, DE
• Dietmar Flubacher · Glückstadt, DE
• Cristina Alonso-Alija · Haan, DE
• Frank Wunder · Wuppertal, DE
• Dieter Lang · Velbert, DE
• Klaus Dembowsky · Boston, US
• Alexander Straub · Wuppertal, DE
• Elisabeth Perzborn · Wuppertal, DE

Key dates

• Filing date: Apr 30, 2002
• Grant date: Jul 19, 2005
• Expiry date: Apr 30, 2022

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention relates to pyrazol pyridine derivatives of formula (I)wherein R1 is a radical of the formula −O—SO2—R3 in which R3 is optionally substituted C1—6—alkyl, optionally substituted C3—8—cycloalkyl, or optionally substituted phenyl; R2 is H, optionally substituted C1—6—alkyl —CO—or optionally substituted C1—6—alkyl—SO2— ; as well as salts, stereoisomers, tautomers, and hydrates thereof. Pharmaceutical compositions containing these materials and methods of using them in medical treatment are also described and claimed.