Transcriptionally-activated AAV inverted terminal repeats (ITRs) for use with recombinant AAV vectors
US6936466B2 · kind B2 · utility
25Cited by
61References
109Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jul 19, 2001 |
| Grant date | Aug 30, 2005 |
| Priority date | — |
| Expiry date | Jul 19, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2830/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention provides transcriptionally-activated AAV ITRs (inverted terminal repeats) which are small and transcriptionally active and uses thereof to optimize the expression of relatively large transgenes packaged in recombinant AAV vectors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.