Chimeric GFP-aequorin as bioluminescent Ca++reporters at the single cell level
US6936475B2 · kind B2 · utility
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25Claims
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Key dates
| Filing date | Dec 2, 2002 |
| Grant date | Aug 30, 2005 |
| Priority date | — |
| Expiry date | Dec 2, 2022 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S930/31
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A modified bioluminescent system comprising a fluorescent molecule covalently linked with a photoprotein, wherein said link between the two proteins has the function to stabilize the modified bioluminescent system and allowing the transfer of the energy by Chemiluminescence Resonance Energy Transfer (CRET).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.