Preparation of rotamer mixtures of pharmaceutical salts
US6936718B2 · kind B2 · utility
2Cited by
2References
39Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 26, 2002 |
| Grant date | Aug 30, 2005 |
| Priority date | — |
| Expiry date | Nov 26, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
In one embodiment, the present invention discloses a process to directly prepare an unequal ratio of specific, preferred rotamer or rotameric pair of an acid salt from a basic compound, by creative choice of a solvent medium. The process is particularly useful in preparing desired rotamers of pharmaceutically useful salts.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.