Nitric oxide-releasing amidine diazeniumdiolates, compositions and uses thereof and method of making same

US6949530B2 · kind B2 · utility

Assignee

• The United States of America, as represented by the Department of Health and Human Services · US

Inventors

• Joseph A. Hrabie · Frederick, US
• Larry K. Keefer · Bethesda, US
• Ernst Arnold · Hagerstown, US

Key dates

• Filing date: Jul 18, 2002
• Grant date: Sep 27, 2005
• Expiry date: Sep 17, 2022

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to nitric oxide-releasing amidine diazeniumdiolates, compositions comprising same, methods of using same, and a method for preparing same from imidate diazeniumdiolates and primary or secondary amines.